Separase

Separase is a caspase-like cysteine protease, which plays a central role in triggering ANAPHASE by cleaving the SCC1/RAD21 subunit of the cohesin complex. Cohesin holds the sister CHROMATIDS together during METAPHASE and its cleavage results in chromosome segregation.

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Cysteine Proteases: 1964
        Cysteine Endopeptidases: 4
        Separase: 54
      - Endopeptidases: 633
        Cysteine Endopeptidases: 4
        Separase: 54
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Cell Cycle Proteins: 807
    - Separase: 54

Germain M Ducos Selected Research

Germain M Ducos Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure